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Monday, January 30, 2012

Weekly Update 4 - Genetics 2

Weekly Update 3 - Genetics II

This week:  Genetic Regulation, Epigenetics, Gene Transfer, Mutation and Bacterial Evolution.

Suggested Readings:
  • Slonczewski and Foster textbook:  
    • Chapter 9: Gene Transfer, Mutations, and Genome Evolution
    • Chapter 10: Molecular Regulation
  • Casadesús J, Low D. Epigenetic Gene Regulation in the Bacterial World. Microbiology and Molecular Biology Reviews. 2006;70(3):830 -856.

Learning Objectives:
  • Be able to describe different ways of regulating gene expression.
  • Be able to describe in detail the regulation of the Lac operon.
  • Be able to describe the regulation of the Trp operon.
  • Be able to describe the function and action of DNA binding proteins.
  • Be able to describe AraC-Like proteins.
  • Be able to describe the regulation of Sigma Factors.
  • Be able to describe Phase Variations.
  • Be able to describe the action of the small RNAs.
  • Be able to describe the concept of epigenetics with at least one example.
  • Be able to describe the concepts of Genomics and Proteomics.
  • Be able to describe the three primary ways of bacterial gene transfer.
  • Be able to describe recombination and mutation.
  • Be able to describe DNA repair mechanisms.
  • Be able to describe Mobile Genetic Elements.
  • Be able to discuss key features in bacterial evolution, and how it differs from eukaryotic evolution.

Administrative Notes:
This is a reminder.  When you want to email me, please email me at rmaxwell@gsu.edu.  I may not get your message if you send it through the social website or uLearn.  To make sure I get it, use my gsu.edu account.

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